The Wyalusing Valley Wine Festival takes place on the grounds of the Wyalusing Valley Museum, behind the big red barn. The museum is located just off Route 6, across from the Wyalusing Valley Jr./Sr. High School on Wyalusing-New Albany Road/SR2010. Wyalusing is located in Bradford County between Towanda and Tunkhannock. We are about 50 miles west of Scranton/Wilkes-Barre, PA; 45 miles southwest of Binghamton, NY; and 65 miles northeast of Williamsport, PA.